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Investigating the pivotal role of gut microbiota in cognitive disorders
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10.60141/AJID/V.2.I.1.9
Investigating the pivotal role of gut microbiota in cognitive disorders
<p><strong>Background:</strong> The human intestine harbors a collection of microorganisms known as intestinal microbiota, which encompasses bacteria, archaea, and eukaryotes. However, bacteria reign supreme as the most prevalent members of the intestinal microbiota. Notably, the gut microbiota plays a crucial role in regulating various physiological functions of the human body. In addition to its influence on digestion, the gut microbiota also exerts control over the function of the brain and central nervous system, earning the enteric nervous system the title of the "second brain." The behavior and mood, as well as the progression of nervous system diseases like multiple sclerosis, autism, Alzheimer's, schizophrenia, and Parkinson's, can potentially be regulated by the intestinal microbiota. Through the intestinal nervous system, production of metabolites, stimulation of entero-endocrine cells, and the immune system, the gut microbiota plays a role in regulating the function of the central nervous system. Disturbances caused by improper nutrition, indiscriminate use of antibiotics, stress, anxiety, and depression are significant factors that can worsen these diseases and disrupt the balance of gut microbiota.</p>
https://creativecommons.org/licenses/by/4.0
2024
Cognitive disorders
microbiota
microbiota-gut-brain axis
Elham
Akbari
Khatam Al-Nabieen University
AF
murtaza.haidary@knu.edu.af
https://orcid.org/0000-0001-7856-8948
<p>Department of Biology and Microbiology, School of Medical Laboratory Technology, Khatam Al-Nabieen University, Kabul, Afghanistan</p>
Dawood
Hossaini
Khatam Al-Nabieen University
AF
murtaza.haidary@knu.edu.af
https://orcid.org/0000-0001-7873-7617
<p>Department of Biology and Microbiology, School of Medical Laboratory Technology, Khatam Al-Nabieen University, Kabul, Afghanistan</p>
Murtaza
Haidary
Khatam Al-Nabieen University
AF
murtaza.haidary@knu.edu.af
https://orcid.org/0000-0002-7273-9088
<p>Research and Technology Center, Khatam Al-Nabieen University, Kabul, Afghanistan.</p>
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Second Volume, First issue, january 2024
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