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Toxo Registry based study-Iran.docx
Authors' commitment and conflict of interests form.docx
Toxo+Registry+based+study-Iran.docx
AJID-O05 Fakhar-for edit 2 july 2025.docx
AJID-O05 Fakhar-for edit 2 july 2025.docx
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10.60141/ajid.119
Sero-Evidence Status of Toxoplasma gondii Infection in Mazandaran Province, Northern Iran: First Population-Based Regional Registry Analysis
<p><strong>Background: </strong><em>Toxoplasma gondii</em> is one of the most common parasitic infections in humans and other vertebrates worldwide. Regional seroprevalence data are critical for targeted interventions. Weaimed to investigate serological evidence of <em>Toxoplasma</em> infection among patients referred to the Iranian National Registry Center for Toxoplasmosis (INRCT) at the Mazandaran University of Medical Sciences (MAZUMS).</p>
<p><strong>Methods: </strong>In this retrospective (descriptive-analytical) study, all patients referred to the INRCT, constitute the study population (underlying diseases/status) throughout 2021-2025. All data including demographic and some related characteristics were collected into a questionnaire and registered at the INRCT in Imam Khomeini Hospital, Sari, northern Iran. The existence of anti-<em>Toxoplasma</em> antibodies (IgG) was explored using a commercially available ELISA kit (PishtazTeb, Iran), based on the manufacturer’s protocol.</p>
<p><strong>Results: </strong>Anti-<em>Toxoplasma</em> IgG were detected among 862/1691 patients (50.98%). The most positive anti-<em>Toxoplasma</em> antibodies were in infertile women and the least were in suicide. IgG seropositivity was more common in females (66.01%) than in males (33.99%) and in 31–40 yr old patients (33.41%) in urban populations (53.71%).</p>
<p><strong>Conclusion: </strong>The findings highlight a high burden of <em>T. gondii</em> infection in northern Iran, with gender, age, and residency as key determinants. Targeted screening and preventive measures are recommended for high-risk groups, including women of reproductive age and immunocompromised populations.</p>
https://creativecommons.org/licenses/by/4.0
Rabeeh Tabaripour, Mahdi Fakhar, Zakaria Zakariaei, Zahra Hosseininejad
2025
Toxoplasma gondii
Seroprevalence
IgG antibodies
Registry-based study
Iran
Epidemiology
Rabeeh
Tabaripour
Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran
IR
r.tabaripour69@gmail.com
Mahdi
Fakhar
Toxoplasmosis Research Center, Communicable Diseases Institute, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
IR
mahdifakhar53@gmail.com
Zakaria
Zakariaei
Toxicology and Forensic Medicine Division, Mazandaran Registry Center for Opioids Poisoning, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran
IR
ali.zakariaei@yahoo.com
Zahra
Hosseininejad
Department of Laboratory Sciences, Estahban Faculty of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
IR
hoseini125@yahoo.com
126
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